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Surrogacy terms D to F: definitions

The short answer

This glossary defines surrogacy, egg donation and IVF terms from D to F in one or two sentences each. Example entries: Directed (known) donation: egg or sperm donation by a person the recipients already know. Egg donor: a screened woman, usually 21 to 30, whose eggs are retrieved to create embryos for another family. Embryo transfer: the 10-minute office procedure that places one thawed embryo in the uterus. Endometrium: the uterine lining, built to 7 millimeters or more before transfer. Escrow: a fund held by an independent licensed agent, financed by the intended parents ($10,000 at match with PLS), that pays the surrogate and vendors on the contract schedule. Euploid: an embryo with a normal chromosome count. FET (frozen embryo transfer): a transfer of a previously vitrified embryo. FDA donor eligibility: federal screening required of every egg and sperm donor.

Written by Nancy Block, RN

Founder and Director. Fertility nurse, 17 years at Northwestern Memorial Hospital. Former President, SEEDS.

Medically reviewed by Mark Silverberg, MD

Last updated

Directed donation, donor agreement, donor compensation

Directed donation

Egg or sperm donation by a person the recipients already know, also called known donation. See known, anonymous and identity-release donors.

Donor agreement

The contract between an egg donor and intended parents covering compensation, confidentiality and parental rights.

Donor compensation

Payment to an egg donor for her time, effort and risk. See egg donor compensation.

Egg donor, egg retrieval, embryo, embryo grading, embryo transfer

Egg donor

A screened woman, usually 21 to 30, whose eggs are retrieved to create embryos for another family. See egg donation.

Egg retrieval

A short procedure under sedation that collects eggs from the ovaries with an ultrasound-guided needle. See the donor process.

Embryo

A fertilized egg in its first days of growth, grown in the lab for 5 to 7 days in IVF.

Embryo grading

The lab's visual score of an embryo's development and appearance. See embryo grading.

Embryo transfer

The roughly 10-minute procedure that places one thawed embryo in the uterus, with no anesthesia.

Endometrium, ERA, escrow, estrogen, euploid

Endometrium

The uterine lining, built to about 7 millimeters or more before transfer.

ERA

Endometrial receptivity analysis: a biopsy taken in a mock cycle to check whether the lining is receptive on the planned transfer day.

Escrow

A fund held by an independent licensed escrow agent, financed by the intended parents, that pays the surrogate and vendors on the contract schedule. With PLS, parents fund $10,000 at match and the balance before medications start. See escrow.

Estrogen

The hormone that builds the uterine lining in a transfer cycle, taken by pill, patch or injection.

Euploid

An embryo with a normal chromosome count on PGT-A testing.

FDA donor eligibility, FET, fertility clinic, fresh cycle, frozen egg bank

FDA donor eligibility

Federal screening and infectious disease testing required of every egg and sperm donor. See donor screening.

FET

Frozen embryo transfer: the transfer of a previously frozen embryo. See the FET protocol.

Fertility clinic

The medical practice that creates embryos, screens the surrogate and performs the transfer.

Fresh cycle

A donor cycle in which your chosen donor is stimulated for you and all her eggs are fertilized for you.

Frozen egg bank

A company that sells a lot of frozen eggs from a donor who has already cycled. A lot is commonly 6 to 8 eggs. See fresh vs frozen.

How to cite this glossary

Cite as Private Label Surrogacy, "Surrogacy terms D to F: definitions," by Nancy Block, RN, medically reviewed by Mark Silverberg, MD, last updated October 14, 2026, privatelabelsurrogacy.com/glossary/surrogacy-terms-d-f/. Previous: terms A to C. Next: terms G to L.

Term Related page Source
Directed donation Donor types ASRM
Embryo transfer, FET FET protocol ASRM, SART
ERA Mock cycle ASRM
Escrow Escrow PLS agreement
FDA donor eligibility Donor screening FDA, ASRM

Sources

Editor notes (D-057): Escrow amount from brief; confirm. SEAM figure stated as 'or more' per brief.

Frequently asked questions

What does escrow protect against?

An agency holding or losing your money. The SEAM escrow collapse of $16 million or more and the Surro Connections failure are why PLS has always used independent licensed escrow.

What is the difference between a fresh cycle and a frozen egg bank?

A fresh cycle stimulates your chosen donor for you and fertilizes all her eggs; a bank sells a frozen lot, commonly 6 to 8 eggs, from a donor who already cycled.

What is an ERA?

Endometrial receptivity analysis, a biopsy taken in a mock cycle to check whether the lining is receptive on the planned transfer day.